What does a Roll Up look like when unrolled? If this is all to much to swallow, maybe try cutting it up. But where to cut?
Once you've filled the roll up, whereabouts can you find the answers to the other set of clues? It all seems the same to me...
The numbered clues form one long string, where the last letter of one clue is the same as the first letter of the next clue. Fill the grid with this string in a spiral pattern, starting at M and ending at N. Now look at opposing spokes: what's missing between them?